Multilocus association mapping using generalized ridge logistic regression

	Multilocus association mapping using generalized ridge logistic regression
	Liu, Zhe 2; Shen, Yuanyuan 3; Ott, Jurg 1; Ott, J (reprint author), Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, 4A Datun Rd, Beijing 100101, Peoples R China.
心理所单位排序	3
摘要	Background: In genome-wide association studies, it is widely accepted that multilocus methods are more powerful than testing single-nucleotide polymorphisms (SNPs) one at a time. Among statistical approaches considering many predictors simultaneously, scan statistics are an effective tool for detecting susceptibility genomic regions and mapping disease genes. In this study, inspired by the idea of scan statistics, we propose a novel sliding window-based method for identifying a parsimonious subset of contiguous SNPs that best predict disease status.
学科领域	Physiological Psychology/biological Psychology
	2011-09-29
语种	英语
发表期刊	BMC BIOINFORMATICS
ISSN	1471-2105
卷号	12
期刊论文类型	Article
URL	查看原文
收录类别	SCI
项目简介	This work has been supported by NSFC grants from the Chinese government (project numbers 30730057 and 30700442) to JO.
WOS记录号	WOS:000295848700001
资助机构	NSFC from the Chinese government [30730057, 30700442]
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/12862
专题	中国科学院心理健康重点实验室
通讯作者	Ott, J (reprint author), Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, 4A Datun Rd, Beijing 100101, Peoples R China.
作者单位	1.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China 2.Univ Chicago, Dept Stat, Chicago, IL 60637 USA 3.Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
推荐引用方式 GB/T 7714	Liu, Zhe,Shen, Yuanyuan,Ott, Jurg,et al. Multilocus association mapping using generalized ridge logistic regression[J]. BMC BIOINFORMATICS,2011,12.
APA	Liu, Zhe,Shen, Yuanyuan,Ott, Jurg,&Ott, J .(2011).Multilocus association mapping using generalized ridge logistic regression.BMC BIOINFORMATICS,12.
MLA	Liu, Zhe,et al."Multilocus association mapping using generalized ridge logistic regression".BMC BIOINFORMATICS 12(2011).

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