Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up

	Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up
	Yin, Jianzhong 1; Xue, Yonggang 1; Lin, Peng 2; Weng, Xuchu3 ; Qi, Ji 1; Yin, JZ (reprint author), Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China.
心理所单位排序	3
摘要	During speech restoration following laryngectomy, language-related cortical areas develop connections with new primary motor neurons. The present study followed up 18 patients after total resection of laryngeal carcinoma. According to an evaluation of pronunciation, patients were assigned to three groups: poor, moderate and good pronunciation. Functional magnetic resonance imaging revealed significant increases in the number of activated voxels and the intensity of activation changes in the left middle frontal gyrus, left precentral gyrus, left postcentral gyrus, left supplementary motor area, left anterior cingulate gyrus and right fusiform gyrus between the moderate pronunciation group compared with the poor and good pronunciation groups. We propose that these brain regions play an important role in the progress of speech restoration, and improvements in pronunciation learning for patients following laryngectomy. However, during the later period of speech restoration, the number of activated voxels and intensity changes in these regions decreased to the level of healthy controls, indicating that the learning and instruction effects weakened once patients had mastered pronunciation techniques.
关键词	magnetic resonance imaging functional laryngeal carcinoma laryngectomy language training neuroplasticity
学科领域	Medical Psychology
	2011-04-15
语种	英语
发表期刊	NEURAL REGENERATION RESEARCH
ISSN	1673-5374
卷号	6 期号:11 页码:834-838
期刊论文类型	Article
URL	查看原文
收录类别	SCI
项目简介	The study was supported by the Natural Science Foundation of Tianjin, No. 06YFJMJC09300.
WOS记录号	WOS:000291416100007
资助机构	Natural Science Foundation of Tianjin [06YFJMJC09300]
引用统计
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/13241
专题	中国科学院心理健康重点实验室
通讯作者	Yin, JZ (reprint author), Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China.
作者单位	1.Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Radiol, Tianjin 300192, Peoples R China 2.Tianjin Med Univ, Cent Clin Coll 1, Tianjin Cent Hosp 1, Dept Otolaryngol, Tianjin 300192, Peoples R China 3.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Yin, Jianzhong,Xue, Yonggang,Lin, Peng,et al. Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up[J]. NEURAL REGENERATION RESEARCH,2011,6(11):834-838.
APA	Yin, Jianzhong,Xue, Yonggang,Lin, Peng,Weng, Xuchu,Qi, Ji,&Yin, JZ .(2011).Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up.NEURAL REGENERATION RESEARCH,6(11),834-838.
MLA	Yin, Jianzhong,et al."Reorganization characteristics of speech cortex during speech restoration following total laryngectomy. A functional magnetic resonance imaging follow-up".NEURAL REGENERATION RESEARCH 6.11(2011):834-838.

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