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Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats
Wang, Yan-Ling1; Wang, Kang1; Yu, Shu-Jing1; Li, Qian1; Li, Na1; Lin, Peng-Yao1; Li, Ming-Ming1; Guo, Jian-You2
摘要Diabetic retinopathy is severe damage to the retina caused by complications of diabetes, and is the prevailing cause of blindness. Accumulating evidence from both animal models and humans suggests that the inflammatory process plays a key role in the development of diabetic retinopathy and is facilitated by innate immune response. The aim of this study was to examine whether the TLR4 signaling pathway was involved in the streptozotocin-induced diabetic rat retina.
关键词Diabetes Diabetic retinopathy Streptozotocin Toll-like receptor 4 TAK-242
2015-03-01
语种英语
发表期刊GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
ISSN0721-832X
卷号253期号:3页码:389-398
期刊论文类型Article
收录类别SCI
WOS记录号WOS:000350510200008
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被引频次:36[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/13496
专题中国科学院心理健康重点实验室
作者单位1.Beijing Capital Med Univ, Affiliated Beijing Friendship Hosp, Dept Ophthalmol, Beijing 100050, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
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Wang, Yan-Ling,Wang, Kang,Yu, Shu-Jing,et al. Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats[J]. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,2015,253(3):389-398.
APA Wang, Yan-Ling.,Wang, Kang.,Yu, Shu-Jing.,Li, Qian.,Li, Na.,...&Guo, Jian-You.(2015).Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats.GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,253(3),389-398.
MLA Wang, Yan-Ling,et al."Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats".GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 253.3(2015):389-398.
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