| 其他摘要 | Currently, the high incidence of cancer has not been overcome. Cancer as a major source of stress could bring a significant psychological impact to patients. The posttraumatic stress disorder (PTSD) is one of the most specific and serious mental health problems. In addition to negative effects, Cancer experience can also bring positive change. Studies have shown that posttraumatic stress disorder and posttraumatic growth will have a significant impact on quality of life. This study focused on 299 hospitalized advanced cancer patients with questionnaires for the study. Objective: To investigate the prevalence and predictive factors of posttraumatic stress disorder (PTSD), posttraumatic growth (PTG) of hospitalized advanced cancer patients, and to analyze the predictive role of PTSD and PTG in quality of life. Methods: A total of 299 participants (188 men, 111 women; mean age=54.44, SD=12.86) were recruited to this survey. 115 digestive oncology, 100 lung cancer, 26 urinary and reproductive system cancer, 25 lymphoma, 23 breast cancer, 3 mediastinal tumor, 2 nervous system tumors, 2 gynecologic oncology, 1 unknown primary tumor, 2 unclear; 103 people diagnosed with the time from 1 to 3 months, 194 people diagnosed with more than 3 months; 2 unclear. The participants were administrated with the Posttraumatic Growth Inventory(PTGI), the PTSD Check List-Specific Version (PCL-S) and EORTC-QLQ-C30. Results (1) There was a total of 73 (25.3%) possible PTSD patients among all participants. The PTSD score of 299 advanced cancer patients was 37.4±14.5. Simple linear regression analysis showed that living area (β=0.180, P<0.05), pain conditions (β=-0.243, P<0.05), ongoing therapy (β=0.176, P<0.05), perceived social support score (β=-0.204, P<0.05), positive response average score (β=-0.149, P<0.05) were significantly influenced the severity of PTSD symptoms. According to multiple linear regression analysis, pain conditions (β=-0.047, P<0.05), ongoing therapy (β=0.135, P<0.05) and living area (β=0.181, P<0.05) could predict for the severity of PTSD symptoms. (2) There was a total of 159 (57.2%) possible PTG patients among all participants. The PTG score of 299 advanced cancer patients was 64.2±20.3.. Simple linear regression analysis showed that living area (β=0.126, P<0.05), perceived social support score (β=0.436, P<0.05), positive response average score (β=0.497, P<0.05) and negative response average score (β=0.252, P<0.05) were significantly influenced PTG. Perceived social support score (β=0.240, P<0.05) and positive response average score (β=0.398, P<0.05) could predict for PTG. (3) In 299 hospitalized advanced cancer patients, the severity of PTSD symptoms could predict QOL’s each dimension (Physical function: β=0.118, P<0.001; role function: β=0.138, P<0.001; emotional function: β=0.095, P<0.001; cognitive function: β=0.105, P<0.001; social function: β=0.139, P<0.001; quality of life: β=0.109, P<0.05); PTG could not predict QOL’s each dimension, PTG could not regulate the effect on PTSD in QOL. Conclusion: （1） PTG was a common psychological phenomenon among hospitalized advanced cancer patients, and the main predictive factors of PTG included living area, perceived social support and positive response. （2） PTSD was a common mental problems among hospitalized advanced cancer patients, and the main predictive factors of PTSD included living area, pain conditions, ongoing therapy, perceived social support and positive response. （3） The severity of PTSD symptoms could well predict QOL while PTG could not predict QOL’s each dimension. PTG could not regulate the effect on PTSD in QOL. |
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