中国科学院心理健康重点实验室知识库

目的探讨长期高海拔暴露对藏族世居者空间工作记忆的影响。方法采用空间工作记忆n-back范式采集了66名长期居住在不同高海拔地区(2900、3700、4200米)藏族世居者的行为与脑电数据,并对脑电数据进行时频分析。结果三个海拔地区的被试在行为数据上无显著差异;海拔4 200米被试的delta频段与theta频段能量值显著低于海拔3 700米和海拔2 900米被试的能量值。结论长期高海拔暴露仅对4 200米海拔地区世居者的反应抑制与信息维持能力产生消极影响,证明4 000米左右海拔是藏族世居者空间工作记忆损伤的海拔阈限。

To explore the effects of long－term high altitude exposure on spatial working memory of Tibetan indigenous residents．Methods The spatial working memory n－back paradigm was used to collect the behavioral and eeg data of 66 Tibetan indigenous residents who lived in Tibet for a long time at different altitudes ( 2900m，3700m，4200m)，and time－frequency analysis was performed on the eeg data．Results There was no significant difference in the behavioral data of the three altitude． The power value of delta and theta frequency in the 4200m was significantly lower than that in the 3 700 m and 2900m．Conclusion Long－term exposure to high altitude only had a negative impact on the response inhibition and information maintenance ability of the Tibetan inhabitants in 4 200 m altitude group，proving that the altitude of about 4 000 m is the altitude threshold of the spatial working memory of the Tibetan inhabitants.

国家自然科学基金项目(No.31660274,31560277);; 西藏大学2019年度科研培育基金项目(ZDTSJH19-09)