Impaired social decision-making in males with methamphetamine use disorder

doi:10.1111/adb.13204

	Impaired social decision-making in males with methamphetamine use disorder
	Ming-Hui Li; Mingming Zhang; Ti-Fei Yuan; Li-Lin Rao
通讯作者	Yuan, Ti-Fei([email protected]) ; Rao, Li-Lin([email protected])
	2022
关键词	computational modelling drift-diffusion model methamphetamine prosociality social cognition
英文摘要	Individuals with methamphetamine use disorder (MUD) commonly exhibit socially problematic behaviours. Investigating the prosocial decision-making of individuals with MUD could enable a better understanding of their impaired social functioning and help improve their social relationships. We conducted two studies to examine the performance of individuals with MUD and healthy controls on a modified dictator game. In Study 1, 55 male individuals with MUD and 34 healthy male participants made a series of choices between two pairs of monetary prizes for themselves and for others. In Study 2, 62 male individuals with MUD and 31 healthy male participants made the same choices as in Study 1 after a brief exposure to methamphetamine-related pictures. In both studies, we consistently found a context dependency of decreased prosociality in individuals with MUD. That is, individuals with MUD made fewer prosocial choices than healthy individuals in disadvantageous contexts (but not advantageous contexts). The results of the computational model suggested that the lower prosociality of individuals with MUD in disadvantageous contexts could be attributed to the lower weight placed on others' benefits. Moreover, when exposed to methamphetamine-related pictures, individuals with MUD showed less caution and slower encoding/motor speed than healthy individuals, and individuals with MUD with a longer history of methamphetamine use tended to respond less cautiously. Our findings provide evidence that in disadvantageous contexts, individuals with MUD show reduced prosociality and less consideration of others' benefits. Identifying the origin of the alterations in prosocial decision-making has implications for diagnosis and treatment.
项目资助者	National Natural Science Foundation of China ; National Science and Technology Innovation 2030 Major Project of China
DOI标识	10.1111/adb.13204
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	实验材料与数据
条目标识符	http://ir.psych.ac.cn/handle/311026/38648
专题	中国科学院心理健康重点实验室
通讯作者	Ti-Fei Yuan; Li-Lin Rao
作者单位	中国科学院心理研究所
推荐引用方式 GB/T 7714	Ming-Hui Li,Mingming Zhang,Ti-Fei Yuan,et al. Impaired social decision-making in males with methamphetamine use disorder. 2022.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Study1_modelEst.RDat（3KB）	实验材料与数据		开放获取	CC BY-NC-SA	浏览下载
Study2_choice.RData（64KB）	实验材料与数据		开放获取	CC BY-NC-SA	浏览下载
Study2_modelEst.RDat（3KB）	实验材料与数据		开放获取	CC BY-NC-SA	浏览下载
Study1_choice.RData（61KB）	实验材料与数据		开放获取	CC BY-NC-SA	浏览下载