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甲基苯丙胺成瘾者复吸的高危及保护性因素调查
其他题名A survey research on the high risk and protective factors of relapse behaviors in methamphetamine addiction
陈俏
导师李勇辉
2020-01
摘要药物成瘾是一种慢性复发性脑疾病。长期毒品滥用造成单胺类递质系统投射的脑区发生功能及结构上的改变,奖赏系统功能紊乱,成瘾者对自然奖赏兴趣减弱,执着于寻求毒品及相关线索带来的更高效的奖赏体验;情绪系统也受到损伤,负性情绪体验增多,易激惹;前额叶皮层区域的损伤使得执行功能下降,难以维持戒断。我国的毒品滥用主要以甲基苯丙胺(又称冰毒)为主,甲基苯丙胺滥用对个人、家庭和社会等各方面都带来严重的挑战。目前针对甲基苯丙胺成瘾的干预和治疗方案还在不断完善和检验中。降低复吸率是戒毒治疗和干预的关键,识别复吸的高危因素有助于预防成瘾复吸,而复吸的保护性因素既能减少复吸可能性,又能缓和高危因素对复吸的影响。探讨甲基苯丙胺成瘾复吸的高危及保护性因素可为预防复吸提供依据,有助于完善社区康复方案。目前研究大都关注复吸的高危因素,对保护性因素的探讨较少。本研究分为三个部分,以期系统探索甲基苯丙胺成瘾复吸的高危及保护性因素。一、对56名甲基苯丙胺成瘾者进行高危及保护性因素访谈。访谈结果发现甲基苯丙胺成瘾复吸的高危因素是同伴诱惑、人际冲突和社会排斥。而复吸的最佳保护性因素是社会支持。二、在文献调研、半结构化访谈和预测试的基础上,初步编制了诱发和影响甲基苯丙胺成瘾复吸的高危及保护性因素调查问卷。诱发因素问卷包含情绪、压力事件、社会支持、线索暴露、生理5个方面,影响因素问卷包含认知和生活状态2个方面。三、采用诱发和影响甲基苯丙胺复吸高危及保护性因素调查问卷对广东和湖南强制隔离戒毒所的371名(其中232名女性)甲基苯丙胺成瘾者进行调研,对复吸的高危及保护性因素进行特异性比较。研究结果显示成瘾严重程度、性别等在复吸因素上存在显著差异。成瘾程度更加严重的个体,负性情绪、毒友诱惑等方面诱发复吸的风险更高。女性更容易因为负性情绪、人际冲突和社会排斥等高危因素导致复吸,而社会支持和工作充实是女性维持戒断的重要保护性因素。更低的教育程度和不稳定的工作状态预示着更严重的社会排斥,复吸的可能性越大。本研究初步形成了预防甲基苯丙胺复吸的高危和保护性因素的基本框架,并强调保护性因素在临床实践中的积极指导意义。需不断完善戒毒人员的社会支持系统,需要有关部门在医疗、教育、就业、享受社会保障等方面对戒毒人员给予必要的指导和帮助。而更好的治疗和干预结果需要个性化了解复吸的高危及保护性因素,也需要个人、家庭和社会共同努力。未来的研究需要在更多地区收集代表性样本进行调研,建立甲基苯丙胺复吸的高危及保护性因素模型,编制信效度良好的量表。
其他摘要Drug addiction is a chronic recurrent brain disease. Long-term drug abuse causes the dysregulation of the reward system, people with drug use disorders reduce interests to natural reward, and seek for drugs and related cues for higher level of reward experience. Drugs also damage the function of emotional system, people with drug use disorders have more negative emotions and become more sensitive to stress events. In addition, drugs impaired the executive function of the prefrontal cortex and decreased its executive function which bring difficulties to drug addicts to maintain abstinence.Methamphetamine abuse brings serious challenges to individuals, families and society in China and other countries. Currently to my knowledge, the effects of intervention and treatment programs for methamphetamine addiction need to be improved and tested. The reduction of relapse rate is the key for effective detoxification treatment and intervention. To explore and analyze the high risk and protective factors of methamphetamine addiction relapse is helpful to improve the detoxification treatment and community rehabilitation program. Identifying the high risk factors of relapse can prevent relapse, and protective factors can reduce the possibility of relapse, as well as decrease the influence of high risk factors on relapse. At present, most of the studies mainly pay attention to the high risk factors of relapse, and there are few discussions on protective factors. This study is divided into three parts in order to systematically explore the high risk and protective factors for relapse behavior of methamphetamine addiction.First, researchers interviewed 56 methamphetamine addicts for investigating high risk and protective factors. The results showed that the high risk factors of methamphetamine addiction relapse were interpersonal conflict, peer temptation and social exclusion. The best protective factor of relapse was social support. Second, On the basis of literature investigation, semi-structured interview and pilot study, the researcher developed the questionnaire of "High Risk And Protective Factors Of Inducing And Influencing Methamphetamine Addiction Relapse". The inducing factors questionnaire includes five sub-questionnaires: emotion, stress events, social support, cue exposure and physiology, and the influencing factors questionnaire includes two sub-questionnaires: cognition and life state. Moreover, the researcher investigated 371 (232 females) people with methamphetamine addiction in the compulsory isolation detoxification centers at Guangdong and Hunan province using the questionnaire of " High Risk And Protective Factors Of Inducing And Influencing Methamphetamine Addiction Relapse ", to understand Specific comparison of high risk and protective factors of relapse .The results showed that there were significant differences in the severity of addiction and gender in relapse factors. The subjects with more severe degree of addiction have higher risk of relapse in terms of negative emotion and peer temptation. Female subjects with methamphetamine addiction were more likely to experience negative emotions, interpersonal conflict and social exclusion as high risk factors. Social support and job fulfillment were protective factors for them to maintain abstinence. Lower levels of education and more unstable working conditions indicate more serious social exclusion leading the greater the likelihood of relapse.This research preliminarily formed a basic framework for the prevention of methamphetamine relapse, and emphasized the guiding significance of protective factors in clinical practice. It is necessary to constantly improve the social support system for drug addicts, and the relevant departments should give necessary guidance and assistance to drug addicts in the aspects of medical treatment, education, employment and social security. And better treatment and intervention results require a understanding of the personalized high risk and protective factors of relapse, as well as the joint efforts of individuals, families and society.In the future, it is necessary to collect representative samples in more areas for survey research, to establish a model of high risk and protective factors for preventing methamphetamine relapse behaviors, and to develop a scale with good reliability and validity.
关键词甲基苯丙胺 复吸 高危因素 保护性因素 调查研究
学位类型硕士
语种中文
学位名称理学硕士
学位专业发展与教育心理学
学位授予单位中国科学院心理研究所
学位授予地点中国科学院心理研究所
文献类型学位论文
条目标识符http://ir.psych.ac.cn/handle/311026/41655
专题健康与遗传心理学研究室
推荐引用方式
GB/T 7714
陈俏. 甲基苯丙胺成瘾者复吸的高危及保护性因素调查[D]. 中国科学院心理研究所. 中国科学院心理研究所,2020.
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