Reversed effects of RU486 and anisomycin on memory retention of light exposure or corticosterone facilitation in the dark-incubated chicks

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	Reversed effects of RU486 and anisomycin on memory retention of light exposure or corticosterone facilitation in the dark-incubated chicks
	Sui, N ; Hu, JF ; Chen, J ; Kuang, PZ ; Joyce, D
摘要	Memory formation for a weak passive avoidance task in the dark-incubated chicks is facilitated by light exposure or corticosterone administration at optimally pre-hatch time points. To explore the potential mechanisms underlying activation of brain memory function development by light or corticosterone exposure during late embryo, steroid receptor antagonist RU486, or protein synthetic inhibitor anisomycin, was administered intraembryonically to the embryos of either only 24-h light-exposure or complete dark-hatched on embryonic day 20 (E20). The results showed that RU486 and anisomycin significantly retarded the facilitated retention both by light and corticosterone exposure in the dark-incubated chicks. They also suggest that the act of corticosterone or light exposure on the development of brain memory function is mediated by the effect of steroid receptor, or afterward on related protein syntheses that is involved in memory formation of post-hatched performance of day-old chicks.; Memory formation for a weak passive avoidance task in the dark-incubated chicks is facilitated by light exposure or corticosterone administration at optimally pre-hatch time points. To explore the potential mechanisms underlying activation of brain memory function development by light or corticosterone exposure during late embryo, steroid receptor antagonist RU486, or protein synthetic inhibitor anisomycin, was administered intraembryonically to the embryos of either only 24-h light-exposure or complete dark-hatched on embryonic day 20 (E20). The results showed that RU486 and anisomycin significantly retarded the facilitated retention both by light and corticosterone exposure in the dark-incubated chicks. They also suggest that the act of corticosterone or light exposure on the development of brain memory function is mediated by the effect of steroid receptor, or afterward on related protein syntheses that is involved in memory formation of post-hatched performance of day-old chicks.
关键词	anisomycin brain corticosterone day-old chicks development memory RU486
学科领域	生理心理学/生物心理学
	2001-12-01
语种	英语
发表期刊	JOURNAL OF PSYCHOPHARMACOLOGY
ISSN	0269-8811
卷号	15 期号:4 页码:287-291
期刊论文类型	Article
收录类别	SCI
WOS记录号	WOS:000172723900011
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/5665
专题	中国科学院心理研究所回溯数据库(1956-2010)
作者单位	1.Acad Sinica, Inst Psychol, Brain & Behav Res Ctr, Beijing, Peoples R China 2.Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
推荐引用方式 GB/T 7714	Sui, N,Hu, JF,Chen, J,et al. Reversed effects of RU486 and anisomycin on memory retention of light exposure or corticosterone facilitation in the dark-incubated chicks[J]. JOURNAL OF PSYCHOPHARMACOLOGY,2001,15(4):287-291.
APA	Sui, N,Hu, JF,Chen, J,Kuang, PZ,&Joyce, D.(2001).Reversed effects of RU486 and anisomycin on memory retention of light exposure or corticosterone facilitation in the dark-incubated chicks.JOURNAL OF PSYCHOPHARMACOLOGY,15(4),287-291.
MLA	Sui, N,et al."Reversed effects of RU486 and anisomycin on memory retention of light exposure or corticosterone facilitation in the dark-incubated chicks".JOURNAL OF PSYCHOPHARMACOLOGY 15.4(2001):287-291.