Disordered connectivity associated with memory deficits in children with autism spectrum disorders | |
Chan, Agnes S.1,2; Han, Yvonne M. Y.1; Sze, Sophia L.1,2; Cheung, Mei-chun3; Leung, Winnie Wing-man1; Chan, Raymond C. K.4,5; To, Cho Yee6; Chan, AS (reprint author), Chinese Univ Hong Kong, Dept Psychol, Neuropsychol Lab, Shatin, Hong Kong, Peoples R China. | |
心理所单位排序 | 4,5 |
摘要 | The present study examined the memory performance and cortical connectivity of children with ASD, and investigated whether the memory deficits exhibited by these children were associated with the cortical connectivity. Twenty-one children with ASD and 21 children with normal development (NC), aged 5-14 years, participated in the study. Each child was administered a neuropsychological battery that included the Test of Nonverbal Intelligence (TONI-Ill), Digit Span test (DS), Rey-Osterrieth Complex Figure Test (Rey-O), and Hong Kong List Learning Test (HKLLT); and an EEG recording session when performing the visual encoding Object Recognition (OR) task. Six neuropsychological measures from the test battery and six EEG coherence measures in the theta band were compared between the children with ASD and normal children. Results indicated that children with ASD performed at comparable levels with normal children in the DS and Rey-O, but were significantly poorer in HKLLT and OR. They also exhibited significantly elevated long-range coherences in the fronto-posterior connections involving the left hemisphere (left anterior-left posterior; left anterior-right posterior). Pearson correlation showed significant negative associations between the anterior-posterior EEG coherences and memory performance. (C) 2011 Elsevier Ltd. All rights reserved. |
关键词 | Autism EEG Coherence Memory Theta Children |
学科领域 | Developmental Psychology |
2011 | |
语种 | 英语 |
发表期刊 | RESEARCH IN AUTISM SPECTRUM DISORDERS |
ISSN | 1750-9467 |
卷号 | 5期号:1页码:237-245 |
期刊论文类型 | Article |
URL | 查看原文 |
收录类别 | SSCI |
资助项目 | 一室陈楚侨课题组 |
WOS记录号 | WOS:000283953800025 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/6903 |
专题 | 健康与遗传心理学研究室 |
通讯作者 | Chan, AS (reprint author), Chinese Univ Hong Kong, Dept Psychol, Neuropsychol Lab, Shatin, Hong Kong, Peoples R China. |
作者单位 | 1.Chinese Univ Hong Kong, Dept Psychol, Neuropsychol Lab, Shatin, Hong Kong, Peoples R China 2.Chinese Univ Hong Kong, Integrat Neuropsychol Rehabil Ctr, Shatin, Hong Kong, Peoples R China 3.Hong Kong Polytech Univ, Inst Text & Clothing, Hong Kong, Hong Kong, Peoples R China 4.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 5.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 6.Univ Michigan, Fac Educ, Ann Arbor, MI 48109 USA |
推荐引用方式 GB/T 7714 | Chan, Agnes S.,Han, Yvonne M. Y.,Sze, Sophia L.,et al. Disordered connectivity associated with memory deficits in children with autism spectrum disorders[J]. RESEARCH IN AUTISM SPECTRUM DISORDERS,2011,5(1):237-245. |
APA | Chan, Agnes S..,Han, Yvonne M. Y..,Sze, Sophia L..,Cheung, Mei-chun.,Leung, Winnie Wing-man.,...&Chan, AS .(2011).Disordered connectivity associated with memory deficits in children with autism spectrum disorders.RESEARCH IN AUTISM SPECTRUM DISORDERS,5(1),237-245. |
MLA | Chan, Agnes S.,et al."Disordered connectivity associated with memory deficits in children with autism spectrum disorders".RESEARCH IN AUTISM SPECTRUM DISORDERS 5.1(2011):237-245. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
WOS000283953800025.p(226KB) | 限制开放 | Apache License | 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论