健康与遗传心理学研究室知识库

Cognitive training for persons with mild cognitive impairment (MCI) has become a hot topic. However to date it remains controversial whether persons with MCI can really benefit from cognitive intervention. We aim to further investigate this by using meta-analysis of seventeen clinical studies of cognitive intervention for MCI. The results demonstrate that after training, patients with MCI improve significantly both in overall cognition and overall self-ratings. Specifically, persons with MCI obtain moderate benefits in language, self-rated anxiety and functional ability, and receive mild benefits in episodic memory, semantic memory, executive functioning/working memory, visuo-spatial ability, attention/processing speed, MMSE, self-rated memory problem, quality of life, activities of daily life and self-rated depression. The results also suggest that persons with MCI benefit from the cognitive intervention in the follow-up data. The present meta-analysis demonstrates that cognitive intervention can be a potential efficient method to enhance cognitive and functional abilities in persons with MCI, although the improvements may be domain-specific. (C) 2010 Elsevier B.V. All rights reserved.

This study was supported by Project for Young Scientists Fund, Institute of Psychology, Chinese Academy of Sciences (Y0CX041S01) and the Special Initiating Funds for Winners of Excellent Doctorate Degree Paper and Presidential Prizes of Chinese Academy of Sciences (Y0CX262B01).