Response inhibition in adolescent earthquake survivors with and without posttraumatic stress disorder: A combined behavioral and ERP study

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	Response inhibition in adolescent earthquake survivors with and without posttraumatic stress disorder: A combined behavioral and ERP study
	Jianhui Wu; Yan Ge; Zhanbiao Shi; Xiaoju Duan; Li Wang; Xianghong Sun; Kan Zhang; Zhang K(张侃)
摘要	The aim of this study was to investigate whether adolescent patients with posttraumatic stress disorder (PTSD) show an impairment of executive control in a response inhibition task and to investigate its neurophysiological correlates using event-related potentials (ERPs). We analyzed data from 25 Wenchuan earthquake survivors between 15 and 19 years of age (16 diagnosed with PTSD) using a Go/NoGo task. The PTSD group made more commission errors than the non-PTSD group, indicating impairment in response inhibition. The PTSD group responded faster to Go trials and there was a significant negative correlation between their reaction time and commission/omission errors, reflecting a speed-accuracy tradeoff for the PTSD group. The PTSD group exhibited a shorter NoGo-N2 latency than the non-PTSD group, suggesting faster monitoring or detection of the response conflict. These results suggest that the impairment of response inhibition in adolescent participants with PTSD is related to their impulsive cognitive functioning.
关键词	Posttraumatic stress disorder Response inhibition Event-related potentials N2
学科领域	创伤心理学
	2010
语种	英语
发表期刊	Neuroscience Letters
ISSN	0304-3940
卷号	486 期号:3 页码:117-121
收录类别	SCI
资助项目	三室张侃课题组
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/7239
专题	中国科学院心理研究所回溯数据库(1956-2010)
通讯作者	Zhang K(张侃)
推荐引用方式 GB/T 7714	Jianhui Wu,Yan Ge,Zhanbiao Shi,et al. Response inhibition in adolescent earthquake survivors with and without posttraumatic stress disorder: A combined behavioral and ERP study[J]. Neuroscience Letters,2010,486(3):117-121.
APA	Jianhui Wu.,Yan Ge.,Zhanbiao Shi.,Xiaoju Duan.,Li Wang.,...&张侃.(2010).Response inhibition in adolescent earthquake survivors with and without posttraumatic stress disorder: A combined behavioral and ERP study.Neuroscience Letters,486(3),117-121.
MLA	Jianhui Wu,et al."Response inhibition in adolescent earthquake survivors with and without posttraumatic stress disorder: A combined behavioral and ERP study".Neuroscience Letters 486.3(2010):117-121.

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