Intermediate Levels of Hippocampal Activity Appear Optimal for Associative Memory Formation

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	Intermediate Levels of Hippocampal Activity Appear Optimal for Associative Memory Formation
	Liu, Xiao 1,2,3; Qin, Shaozheng 1,4; Rijpkema, Mark 1; Luo, Jing2 ; Fernandez, Guillen 1,5; Luo J(罗劲)
摘要	Background: It is well established that hippocampal activity is positively related to effective associative memory formation. However, in biological systems often optimal levels of activity are contrasted by both sub-and supra-optimal levels. Suboptimal levels of hippocampal activity are commonly attributed to unsuccessful memory formation, whereas the supraoptimal levels of hippocampal activity related to unsuccessful memory formation have been rarely studied. It is still unclear under what circumstances such supra-optimal levels of hippocampal activity occur. To clarify this issue, we aimed at creating a condition, in which supra-optimal hippocampal activity is associated with encoding failure. We assumed that such supra-optimal activity occurs when task-relevant information is embedded in task-irrelevant, distracting information, which can be considered as noise.
学科领域	认知神经科学
	2010-10-01
语种	英语
发表期刊	PLOS ONE
ISSN	1932-6203
卷号	5 期号:10
期刊论文类型	Article
收录类别	SCI
资助项目	一室罗劲课题组
WOS记录号	WOS:000282359300031
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/7263
专题	中国科学院心理研究所回溯数据库(1956-2010)
通讯作者	Luo J(罗劲)
作者单位	1.Radboud Univ Nijmegen, Ctr Cognit Neuroimaging, Donders Inst Brain Cognit & Behav, NL-6525 ED Nijmegen, Netherlands 2.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100101, Peoples R China 4.Radboud Univ Nijmegen, Med Ctr, Dept Neurol, NL-6525 ED Nijmegen, Netherlands 5.Radboud Univ Nijmegen, Dept Cognit Neurosci, Donders Inst Brain Cognit & Behav, Med Ctr, NL-6525 ED Nijmegen, Netherlands
第一作者单位	中国科学院心理研究所
推荐引用方式 GB/T 7714	Liu, Xiao,Qin, Shaozheng,Rijpkema, Mark,et al. Intermediate Levels of Hippocampal Activity Appear Optimal for Associative Memory Formation[J]. PLOS ONE,2010,5(10).
APA	Liu, Xiao,Qin, Shaozheng,Rijpkema, Mark,Luo, Jing,Fernandez, Guillen,&罗劲.(2010).Intermediate Levels of Hippocampal Activity Appear Optimal for Associative Memory Formation.PLOS ONE,5(10).
MLA	Liu, Xiao,et al."Intermediate Levels of Hippocampal Activity Appear Optimal for Associative Memory Formation".PLOS ONE 5.10(2010).

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