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Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation 期刊论文
PSYCHONEUROENDOCRINOLOGY, 2020, 卷号: 113, 页码: 10
作者:  Zhang, Juntao;  Lin, Wenjuan;  Tang, Mingming;  Zhao, Yawei;  Zhang, Ke;  Wang, Xiaqing;  Li, Yingcong
Adobe PDF(2481Kb)  |  收藏  |  浏览/下载：662/2  |  提交时间：2020/05/18
Neuroinflammation  Depressive-like behavior  JNK  Proinflammatory cytokines  Glucocorticoid receptor  
Effect of Toll-like receptor 4 on depressive-like behaviors induced by chronic social defeat stress 期刊论文
BRAIN AND BEHAVIOR, 2020, 页码: 10
作者:  Zhang, Ke;  Lin, Wenjuan;  Zhang, Juntao;  Zhao, Yawei;  Wang, Xiaqing;  Zhao, Mei
Adobe PDF(904Kb)  |  收藏  |  浏览/下载：620/0  |  提交时间：2020/02/29
behavioral despair  chronic social defeat stress  depression  inflammation  TLR4  
Transient upregulation of immune activity induced by adolescent social stress is involved in cognitive deficit in adult male mice and early intervention with minocycline 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 374, 页码: 7
作者:  Zhang, Yu;  Xu, Hang;  Wang, Jiesi;  Ren, Fengyan;  Shao, Feng;  Ellenbroek, Bart;  Lin, Wenjuan;  Wang, Weiwen
收藏  |  浏览/下载：604/0  |  提交时间：2020/05/18
Adolescent social stress  Medial prefrontal cortex (mPFC)  Microglia  Tumor necrosis factor alpha (TNF alpha)  Cognitive flexibility  
Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression 期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2018, 卷号: 12, 页码: 14
作者:  Tang, Ming-ming;  Lin, Wen-juan;  Pan, Yu-qin;  Li, Ying-cong
Adobe PDF(4947Kb)  |  收藏  |  浏览/下载：380/1  |  提交时间：2018/09/10
Fibroblast Growth Factor 2  Microglia  Depressive-like Behavior  Neuroinflammation  Cytokines  Cx3cl1  Hippocampus  
Blocking p38 Signaling Reduces the Activation of Pro-inflammatory Cytokines and the Phosphorylation of p38 in the Habenula and Reverses Depressive-Like Behaviors Induced by Neuroinflammation 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 1-14
作者:  Zhao, Ya-wei;  Pan, Yu-qin;  Tang, Ming-ming;  Lin, Wen-juan
Adobe PDF(3912Kb)  |  收藏  |  浏览/下载：401/1  |  提交时间：2018/07/02
depression  p38  neuroinflammation  habenula  fluoxetine  SB203580  
抑郁症研究和治疗的新靶标:JNK信号通路的作用 期刊论文
科学通报, 2018, 卷号: 63, 期号: 20, 页码: 1998 ~ 2009
作者:  张军涛;  林文娟
Adobe PDF(2945Kb)  |  收藏  |  浏览/下载：336/1  |  提交时间：2018/10/26
抑郁症  C-jun氨基端激酶  神经萎缩  神经发生  突触可塑性  神经炎症  兴奋性毒性  糖皮质激素抵抗  
Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by neuroinflammation 期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2017, 卷号: 66, 期号: 0, 页码: 322-331
作者:  Tang, Ming-ming;  Lin, Wen-juan;  Zhang, Jun-tao;  Zhao, Ya-wei;  Li, Ying-cong
Adobe PDF(2700Kb)  |  收藏  |  浏览/下载：371/2  |  提交时间：2017/12/18
Neuroinflammation  Depressive-like behavior  Neurogenesis  Fibroblast growth factor 2  Extracellular signal-regulated kinase 1/2  
中枢免疫失衡与认知功能障碍:聚焦TNFα的作用 期刊论文
心理科学进展, 2017, 卷号: 25, 期号: 12, 页码: 2036–2042
作者:  张瑜;  林文娟;  王玮文
Adobe PDF(445Kb)  |  收藏  |  浏览/下载：435/4  |  提交时间：2017/11/30
内稳态  TNFα  应激  突触可塑性  认知功能  
Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression 期刊论文
PHYSIOLOGY & BEHAVIOR, 2016, 卷号: 161, 期号: 0, 页码: 166-173
作者:  Tang, Ming-ming;  Lin, Wen-juan;  Pan, Yu-qin;  Guan, Xi-ting;  Li, Ying-cong
Adobe PDF(1272Kb)  |  收藏  |  浏览/下载：438/1  |  提交时间：2016/07/14
Depressive-like Behavior  Neuroinflammation  Neurogenesis  Pro-inflammatory Cytokine  Lipopolysaccharide  
An Animal Model of Depression Induced by Central Inflammation 期刊论文
INTERNATIONAL JOURNAL OF PSYCHOLOGY, 2016, 卷号: 51, 期号: 增刊: 1, 页码: 880-880
作者:  Lin, WJ (Lin, Wenjuan);  Tang, MM (Tang, Mingming);  Pan, YQ (Pan, Yuqin)
收藏  |  浏览/下载：214/0  |  提交时间：2018/05/04