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Targeted re-sequencing of linkage region on 2q21 identifies a novel functional variant for hip and knee osteoarthritis 期刊论文
OSTEOARTHRITIS AND CARTILAGE, 2016, 卷号: 24, 期号: 4, 页码: 655-663
作者:  Taipale, M.;  Jakkula, E.;  Kamarainen, O. -P;  Gao, P.;  Skarp, S.;  Barral, S.;  Kiviranta, I.;  Kroger, H.;  Ott, J.;  Wei, G. -H.;  Ala-Kokko, L.;  Mannikko, M.
Adobe PDF(595Kb)  |  收藏  |  浏览/下载:367/1  |  提交时间:2016/05/09
Osteoarthritis  Hip  Knee  Linkage analysis  Next generation sequencing  Enhancer element  
Heritability and familiality of neurological soft signs: evidence from healthy twins, patients with schizophrenia and non-psychotic first-degree relatives 期刊论文
PSYCHOLOGICAL MEDICINE, 2016, 卷号: 46, 期号: 1, 页码: 117-123
作者:  Xu, T.;  Wang, Y.;  Li, Z.;  Huang, J.;  Lui, S. S. Y.;  Tan, S. -P.;  Yu, X.;  Cheung, E. F. C.;  He, M. -G.;  Ott, J.;  Gur, R. E.;  Chan, R. C. K.
Adobe PDF(208Kb)  |  收藏  |  浏览/下载:456/8  |  提交时间:2016/02/15
Endophenotypes  familiality  healthy twins  heritability  neurological soft signs  
The ADAMTS1 Gene Is Associated with Familial Mandibular Prognathism 期刊论文
JOURNAL OF DENTAL RESEARCH, 2015, 卷号: 94, 期号: 9, 页码: 1196-1201
作者:  X. Guan;  Y. Song;  J. Ott;  Y. Zhang;  C. Li;  T. Xin;  Z. Li;  Y. Gan;  J. Li;  S. Zhou;  Y. Zhou
Adobe PDF(384Kb)  |  收藏  |  浏览/下载:349/1  |  提交时间:2018/09/06
Whole Genome Analysis  Snv  Craniofacial Biology/genetics  Orthodontic(s)  Molecular Genetics  Bioinformatics  
Genetic linkage analysis in the age of whole-genome sequencing 期刊论文
NATURE REVIEWS GENETICS, 2015, 卷号: 16, 期号: 5, 页码: 275-284
作者:  Ott, Jurg;  Wang, Jing;  Leal, Suzanne M.
Adobe PDF(366Kb)  |  收藏  |  浏览/下载:539/69  |  提交时间:2015/09/10
Stress-related genes and heroin addiction: A role for a functional FKBP5 haplotype 期刊论文
PSYCHONEUROENDOCRINOLOGY, 2014, 卷号: 45, 期号: 0, 页码: 67-76
作者:  Levran, O.;  Peles, E.;  Randesi, M.;  Li, Y.;  Rotrosen, J.;  Ott, J.;  Adelson, M.;  Kreek, M. J.
Adobe PDF(521Kb)  |  收藏  |  浏览/下载:343/2  |  提交时间:2015/09/18
Genetic Variants  Association Study  Heroin Addiction  Stress  Hpa Axis  Glucocorticoid Sensitivity  Fkbp5  Avpr1a  Gal  
SELF ADMINISTRATION OF OXYCODONE BY ADOLESCENT AND ADULT MICE AFFECTS STRIATAL NEUROTRANSMITTER RECEPTOR GENE EXPRESSION 期刊论文
NEUROSCIENCE, 2014, 卷号: 258, 期号: 0, 页码: 280-291
作者:  Mayer-Blackwell, B.;  Schlussman, S. D.;  Butelman, E. R.;  Ho, A.;  Ott, J.;  Kreek, M. J.;  Zhang, Y.
Adobe PDF(837Kb)  |  收藏  |  浏览/下载:318/7  |  提交时间:2015/09/18
oxycodone  adolescent  adult  self administration  neurotransmitter receptor gene expression  dorsal striatum  
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjogren's syndrome at 7q11.23 期刊论文
NATURE GENETICS, 2013, 卷号: 45, 期号: 11, 页码: 1361-+
作者:  Li, Yongzhe;  Zhang, Kunlin;  Chen, Hua;  Sun, Fei;  Xu, Juanjuan;  Wu, Ziyan;  Li, Ping;  Zhang, Liuyan;  Du, Yang;  Luan, Haixia;  Li, Xi;  Wu, Lijun;  Li, Hongbin;  Wu, Huaxiang;  Li, Xiangpei;  Li, Xiaomei;  Zhang, Xiao;  Gong, Lu;  Dai, Lie;  Sun, Lingyun;  Zuo, Xiaoxia;  Xu, Jianhua;  Gong, Huiping;  Li, Zhijun;  Tong, Shengquan;  Wu, Min;  Li, Xiaofeng;  Xiao, Weiguo;  Wang, Guochun;  Zhu, Ping;  Shen, Min;  Liu, Shengyun;  Zhao, Dongbao;  Liu, Wei;  Wang, Yi;  Huang, Cibo;  Jiang, Quan;  Liu, Guijian;  Liu, Bin;  Hu, Shaoxian;  Zhang, Wen;  Zhang, Zhuoli;  You, Xin;  Li, Mengtao;  Hao, Weixin;  Zhao, Cheng;  Leng, Xiaomei;  Bi, Liqi;  Wang, Yongfu;  Zhang, Fengxiao;  Shi, Qun;  Qi, Wencheng;  Zhang, Xuewu;  Jia, Yuan;  Su, Jinmei;  Li, Qin;  Hou, Yong;  Wu, Qingjun;  Xu, Dong;  Zheng, Wenjie;  Zhang, Miaojia;  Wang, Qian;  Fei, Yunyun;  Zhang, Xuan;  Li, Jing;  Jiang, Ying;  Tian, Xinping;  Zhao, Lidan;  Wang, Li;  Zhou, Bin;  Li, Yang;  Zhao, Yan;  Zeng, Xiaofeng;  Ott, Jurg;  Wang, Jing;  Zhang, Fengchun
Adobe PDF(371Kb)  |  收藏  |  浏览/下载:668/12  |  提交时间:2015/05/18
Polymorphisms of the Kappa Opioid Receptor and Prodynorphin Genes: HIV Risk and HIV Natural History 期刊论文
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2013, 卷号: 63, 期号: 1, 页码: 17-26
作者:  Proudnikov, Dmitri;  Randesi, Matthew;  Levran, Orna;  Yuferov, Vadim;  Crystal, Howard;  Ho, Ann;  Ott, Jurg;  Kreek, Mary J.;  Proudnikov, D (reprint author), Rockefeller Univ, Lab Biol Addict Dis, 1230 York Ave,Box 171, New York, NY 10065 USA.
Adobe PDF(2239Kb)  |  收藏  |  浏览/下载:400/0  |  提交时间:2015/05/19
polymorphism  SNP  viral load  CD4 count  WIHS  OPRK1  PDYN  
Dysfunctional nitric oxide signalling increases risk of myocardial infarction 期刊论文
NATURE, 2013, 卷号: 504, 期号: 7480
作者:  Erdmann, Jeanette;  Stark, Klaus;  Esslinger, Ulrike B.;  Rumpf, Philipp Moritz;  Koesling, Doris;  de Wit, Cor;  Kaiser, Frank J.;  Braunholz, Diana;  Medack, Anja;  Fischer, Marcus;  Zimmermann, Martina E.;  Tennstedt, Stephanie;  Graf, Elisabeth;  Eck, Sebastian;  Aherrahrou, Zouhair;  Nahrstaedt, Janja;  Willenborg, Christina;  Bruse, Petra;  Braenne, Ingrid;  Noethen, Markus M.;  Hofmann, Per;  Braund, Peter S.;  Mergia, Evanthia;  Reinhard, Wibke;  Burgdorf, Christof;  Schreiber, Stefan;  Balmforth, Anthony J.;  Hall, Alistair S.;  Bertram, Lars;  Steinhagen-Thiessen, Elisabeth;  Li, Shu-Chen;  Maerz, Winfried;  Reilly, Muredach;  Kathiresan, Sekar;  McPherson, Ruth;  Walter, Ulrich;  Ott, Jurg;  Samani, Nilesh J.;  Strom, Tim M.;  Meitinger, Thomas;  Hengstenberg, Christian;  Schunkert, Heribert;  CARDIoGRAM;  Hengstenberg, C (reprint author), Deutsch Herzzentrum Munich, D-80636 Munich, Germany.
Adobe PDF(602Kb)  |  收藏  |  浏览/下载:536/0  |  提交时间:2015/05/19
MK4MDD: A Multi-Level Knowledge Base and Analysis Platform for Major Depressive Disorder 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 10, 页码: e46335
作者:  Guo, Liyuan;  Zhang, Weina;  Chang, Suhua;  Zhang, Liuyan;  Ott, Jurg;  Wang, Jing;  Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
Adobe PDF(694Kb)  |  收藏  |  浏览/下载:375/0  |  提交时间:2015/08/26