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HDR: a statistical two-step approach successfully identifies disease genes in autosomal recessive families 期刊论文
JOURNAL OF HUMAN GENETICS, 2016, 卷号: 61, 期号: 11, 页码: 959-963
作者:  Imai, Atsuko;  Kohda, Masakazu;  Nakaya, Akihiro;  Sakata, Yasushi;  Murayama, Kei;  Ohtake, Akira;  Lathrop, Mark;  Okazaki, Yasushi;  Ott, Jurg
Adobe PDF(1538Kb)  |  收藏  |  浏览/下载：158/0  |  提交时间：2017/02/06
Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence 期刊论文
DRUG AND ALCOHOL DEPENDENCE, 2016, 卷号: 168, 期号: 0, 页码: 164-169
作者:  Randesi, Matthew;  van den Brink, Wim;  Levran, Orna;  Blanken, Peter;  Butelman, Eduardo R.;  Yuferov, Vadim;  da Rosa, Joel Correa;  Ott, Jurg;  van Ree, Jan M.;  Kreek, Mary Jeanne
Adobe PDF(606Kb)  |  收藏  |  浏览/下载：380/2  |  提交时间：2016/12/26
Heroin Addiction  Non-dependent Opioid Use  Heroin-assisted Treatment  Opioid Genes  Rs2236861  
African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction 期刊论文
PHARMACOGENOMICS, 2016, 卷号: 17, 期号: 9, 页码: 995-1003
作者:  Levran, Orna;  Randesi, Matthew;  Peles, Einat;  da Rosa, Joel Correa;  Ott, Jurg;  Rotrosen, John;  Adelson, Miriam;  Kreek, Mary Jeanne
Adobe PDF(1018Kb)  |  收藏  |  浏览/下载：349/1  |  提交时间：2016/09/05
African Ancestry  Cholinergic Receptors  Chrm4  Cocaine Addiction  Opioid Addiction  
Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry 期刊论文
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2016, 卷号: 64, 期号: 0, 页码: 118-123
作者:  Levran, Orna;  Peles, Einat;  Randesi, Matthew;  da Rosa, Joel Correa;  Ott, Jurg;  Rotrosen, John;  Adelson, Miriam;  Kreek, Mary Jeanne
Adobe PDF(355Kb)  |  收藏  |  浏览/下载：377/2  |  提交时间：2015/12/07
Addiction  African Americans  Cocaine  GAD1, glutamate, GABA  Heroin  
Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry 会议论文
CNS NEUROSCIENCE & THERAPEUTICS, 不详, 不详
作者:  Levran, O (Levran, Orna);  Peles, E (Peles, Einat);  Randesi, M (Randesi, Matthew);  da Rosa, JC (da Rosa, Joel Correa);  Ott, J (Ott, Jurg);  Rotrosen, J (Rotrosen, John);  Rotrosen, J (Rotrosen, John);  Kreek, MJ (Kreek, Mary Jeanne)
收藏  |  浏览/下载：385/0  |  提交时间：2018/08/29
African Americans  Cocaine Addiction  Heroin Addiction  Signal Transduction  Synaptic Plasticity  
Common Regulatory Variants of CYFIP1 Contribute to Susceptibility for Autism Spectrum Disorder (ASD) and Classical Autism 期刊论文
ANNALS OF HUMAN GENETICS, 2015, 卷号: 79, 期号: 5, 页码: 329-340
作者:  Wang, Jian;  Tao, Yu;  Song, Fan;  Sun, Yue;  Ott, Jurg;  Saffen, David
Adobe PDF(523Kb)  |  收藏  |  浏览/下载：390/8  |  提交时间：2015/12/07
CYFIP1  autism spectrum disorder  regulatory genetic variant  expression quantitative locus (eQTL)  
Leveling the Playing Field in Homozygosity Mapping Using Map Distances 期刊论文
ANNALS OF HUMAN GENETICS, 2015, 卷号: 79, 期号: 5, 页码: 366-372
作者:  Li, Yi;  Cagirici, Halise Busra;  Horpaopan, Sukanya;  Ott, Jurg;  Imai, Atsuko;  Majewski, Jacek;  Lathrop, Mark
Adobe PDF(271Kb)  |  收藏  |  浏览/下载：345/5  |  提交时间：2015/12/07
Homozygosity mapping  linkage disequilibrium  recombination  
Beyond Homozygosity Mapping: Family-Control analysis based on Hamming distance for prioritizing variants in exome sequencing 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5, 期号: 0, 页码: 12028
作者:  Imai, Atsuko;  Nakaya, Akihiro;  Fahiminiya, Somayyeh;  Tetreault, Martine;  Majewski, Jacek;  Sakata, Yasushi;  Takashima, Seiji;  Lathrop, Mark;  Ott, Jurg
Adobe PDF(323Kb)  |  收藏  |  浏览/下载：366/3  |  提交时间：2015/09/08
Overlapping Dopaminergic Pathway Genetic Susceptibility to Heroin and Cocaine Addictions in African Americans 期刊论文
ANNALS OF HUMAN GENETICS, 2015, 卷号: 79, 期号: 3, 页码: 188-198
作者:  Levran, Orna;  Randesi, Matthew;  da Rosa, Joel Correa;  Ott, Jurg;  Rotrosen, John;  Adelson, Miriam;  Kreek, Mary Jeanne
Adobe PDF(427Kb)  |  收藏  |  浏览/下载：370/3  |  提交时间：2015/09/10
Dopaminergic pathway  polymorphism  heroin addiction  cocaine addiction  African Americans  DRD1  DRD2  COMT Val158Met  rs5326  rs1075650  rs2283265  
Genetic linkage analysis in the age of whole-genome sequencing 期刊论文
NATURE REVIEWS GENETICS, 2015, 卷号: 16, 期号: 5, 页码: 275-284
作者:  Ott, Jurg;  Wang, Jing;  Leal, Suzanne M.
Adobe PDF(366Kb)  |  收藏  |  浏览/下载：539/69  |  提交时间：2015/09/10