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Ribosylation-Derived Advanced Glycation End Products Induce Tau Hyperphosphorylation Through Brain-Derived Neurotrophic Factor Reduction 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2019, 卷号: 71, 期号: 1, 页码: 291-305
作者:  Wu, Beibei;  Wang, Yujing;  Shi, Chenggang;  Chen, Yao;  Yu, Lexiang;  Li, Juan;  Li, Weiwei;  Wei, Yan;  He, Rongqiao
收藏  |  浏览/下载:651/0  |  提交时间:2019/10/25
Advanced glycation end products  brain-derived neurotrophic factor  GSK-3 beta oxidative stress  ribosylation  tau hyperphosphorylation  
GRP78 protects CHO cells from ribosylation 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2018, 卷号: 1865, 期号: 4, 页码: 629-637
作者:  Wu, Beibei;  Yu, Lexiang;  Hu, Pingdong;  Lu, Yang;  Li, Juan;  Wei, Yan;  He, Rongqiao;  Y. Wei;  R. He
Adobe PDF(1104Kb)  |  收藏  |  浏览/下载:391/1  |  提交时间:2018/05/28
D-Ribose  GRP78  Glycation  AGEs  Cytotoxicity  
Gavage of D-Ribose induces A beta-like deposits, Tau hyperphosphorylation as well as memory loss and anxiety-like behavior in mice 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34128-34142
作者:  Wu, Beibei;  Wei, Yan;  Wang, Yujing;  Su, Tao;  Zhou, Lei;  Liu, Ying;  He, Rongqiao
Adobe PDF(3398Kb)  |  收藏  |  浏览/下载:345/5  |  提交时间:2016/01/18
D-ribose  Memory Impairment  Tau Hyperphosphorylation  a Beta-like Deposition  Anxiety-like Behavior  Gerotarget  
Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII 期刊论文
AGING CELL, 2015, 卷号: 14, 期号: 5, 页码: 754-763
作者:  Wei, Yan;  Han, Chanshuai;  Wang, Yujing;  Wu, Beibei;  Su, Tao;  Liu, Ying;  He, Rongqiao
Adobe PDF(2046Kb)  |  收藏  |  浏览/下载:352/6  |  提交时间:2015/12/07
hyperphosphorylation  ribosylation  Tau protein  
Agerelated formaldehyde interferes with DNA methyltransferase function causing memory loss in Alzheimers disease 期刊论文
Neurobiology of Aging, 2015, 卷号: 36, 期号: 1, 页码: 100-110
作者:  Zhiqian Tong;  Chanshuai Han;  Min Qiang;  Weishan Wang;  Jihui Lv;  Shouzi Zhang;  \Wenhong Luo;  Hui Li;  Hongjun Luo;  Jiangning Zhou;  Beibei Wu;  Tao Su;  Xu Yang;  Xiaomin Wang;  Ying Liu;  Rongqiao He;  R. He
Adobe PDF(3117Kb)  |  收藏  |  浏览/下载:499/0  |  提交时间:2018/04/25
Endogenous formaldehyde  DNA methyltransfarases (DNMTs  Topographic amnesia  Alzheimer’s disease (AD)  
Aging-associated excess formaldehyde leads to spatial memory deficits 期刊论文
SCIENTIFIC REPORTS, 2013, 卷号: 3
作者:  Tong, Zhiqian;  Han, Chanshuai;  Luo, Wenhong;  Li, Hui;  Luo, Hongjun;  Qiang, Min;  Su, Tao;  Wu, Beibei;  Liu, Ying;  Yang, Xu;  Wan, You;  Cui, Dehua;  He, Rongqiao
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载:333/3  |  提交时间:2015/05/18