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Nardostachys jatamansi and levodopa combination alleviates Parkinson's disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways 期刊论文
PHARMACEUTICAL BIOLOGY, 2023, 卷号: 61, 期号: 1, 页码: 1175-1185
作者:  Li, Jiayuan;  Yu, Jiahe;  Guo, Jianyou;  Liu, Jinfeng;  Wan, Guohui;  Wei, Xiaojia;  Yang, Xue;  Shi, Jinli
Adobe PDF(3752Kb)  |  收藏  |  浏览/下载:153/0  |  提交时间:2023/10/09
Dyskinesia  neurotransmitters  dopaminergic neurons  nardosinone  molecular docking  oxidative stress  neuroinflammation  >  
11-Ethoxyviburtinal improves chronic restraint stress-induced anxiety-like behaviors in gender-specific mice via PI3K/Akt and E-2/ER beta signaling pathways 期刊论文
PHYTOTHERAPY RESEARCH, 2023, 页码: 17
作者:  Lyu, Yan;  Wei, Xiaojia;  Yang, Xue;  Li, Jiayuan;  Wan, Guohui;  Wang, Yuqing;  Hao, Zhuangzhuang;  Lu, Yifan;  Guo, Jianyou;  Shi, Jinli
Adobe PDF(4280Kb)  |  收藏  |  浏览/下载:142/0  |  提交时间:2023/10/09
11-ethoxyviburtinal  antagonists  anxiety disorder  estrogen receptor beta  PI3K-Akt signaling pathway  the male and female mice  
Targeting NMDA Receptors in Emotional Disorders: Their Role in Neuroprotection 期刊论文
BRAIN SCIENCES, 2022, 卷号: 12, 期号: 10, 页码: 17
作者:  Wang, Siqi;  Bian, Lihua;  Yin, Yi;  Guo, Jianyou
Adobe PDF(533Kb)  |  收藏  |  浏览/下载:126/0  |  提交时间:2022/11/27
NMDAR  depression  anxiety  neuroprotection  
Dose Optimization of Anxiolytic Compounds Group in Valeriana jatamansi Jones and Mechanism Exploration by Integrating Network Pharmacology and Metabolomics Analysis 期刊论文
BRAIN SCIENCES, 2022, 卷号: 12, 期号: 5, 页码: 21
作者:  Zhao, Chengbowen;  Wei, Xiaojia;  Guo, Jianyou;  Ding, Yongsheng;  Luo, Jing;  Yang, Xue;  Li, Jiayuan;  Wan, Guohui;  Yu, Jiahe;  Shi, Jinli
Adobe PDF(8347Kb)  |  收藏  |  浏览/下载:166/0  |  提交时间:2022/07/18
Valeriana jatamansi Jones  anxiety disorder  network pharmacology  metabolomics  arachidonic acid metabolism