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Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells 期刊论文
Frontiers in Neuroscience, 2017, 卷号: 10, 期号: 0, 页码: 598
作者:  He, Xiaping;  Li, Zhenhui;  Rizak, Joshua D.;  Wu, Shihao;  Wang, Zhengbo;  He, Rongqiao;  Su, Min;  Qin, Dongdong;  Wang, Jingkun;  Hu, Xintian;  Dongdong Qin;  Jingkun Wang;  Xintian Hu
Adobe PDF(3629Kb)  |  收藏  |  浏览/下载:423/1  |  提交时间:2017/03/13
Alzheimer's disease  formaldehyde  resveratrol  tau protein  GSK-3 beta  CaMKII  PP2A  
Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII 期刊论文
AGING CELL, 2015, 卷号: 14, 期号: 5, 页码: 754-763
作者:  Wei, Yan;  Han, Chanshuai;  Wang, Yujing;  Wu, Beibei;  Su, Tao;  Liu, Ying;  He, Rongqiao
Adobe PDF(2046Kb)  |  收藏  |  浏览/下载:352/6  |  提交时间:2015/12/07
hyperphosphorylation  ribosylation  Tau protein  
Hyperphosphorylation Results in Tau Dysfunction in DNA Folding and Protection 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2013, 卷号: 37, 期号: 3, 页码: 551-563
作者:  Lu, Yang;  He, Hai-Jin;  Zhou, Jun;  Miao, Jun-Ye;  Lu, Jing;  He, Ying-Ge;  Pan, Rong;  Wei, Yan;  Liu, Ying;  He, Rong-Qiao;  He, RQ (reprint author), Chinese Acad Sci, State Key Lab Brain & Cognit Sci, Inst Biophys, 15 Datun Rd, Beijing 100101, Peoples R China.
Adobe PDF(611Kb)  |  收藏  |  浏览/下载:400/0  |  提交时间:2015/05/19
Alzheimer's disease  DNA protection  formaldehyde  GSK-3 beta  phosphorylation  tau hyperphosphorylation  tau protein  tauopathy  
Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 8, 页码: 4102-4116
作者:  Lu, Jing;  Miao, Junye;  Su, Tao;  Liu, Ying;  He, Rongqiao;  He, RQ (reprint author), Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, 15 Datun Rd, Beijing 100101, Peoples R China.
Adobe PDF(3301Kb)  |  收藏  |  浏览/下载:377/1  |  提交时间:2015/05/19
Formaldehyde  Tau hyperphosphorylation  GSK-3 beta  Nuclear accumulation  Protein polymerization  Tauopathy  
d-Ribosylated Tau forms globular aggregates with high cytotoxicity 期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2009, 卷号: 66, 期号: 15, 页码: 2559-2571
作者:  Chen, Lan;  Wei, Yan;  Wang, Xueqing;  He, Rongqiao;  R. Q. He
浏览  |  Adobe PDF(685Kb)  |  收藏  |  浏览/下载:360/56  |  提交时间:2011/08/22
D-Ribose  Tau protein  Glycation  Aggregation  Cytotoxicity