Institutional Repository, Institute of Psychology, Chinese Academy of Sciences
The Role of Orexin in Stress | |
Wei Chu-Guang1,2; Li Yong-Hui1; Han Jin1,2; Wang Hui-Ying1,2; Sui Nan1 | |
摘要 | Orexins (hypocretins) are novel neuropeptides released by some neurons identified in lateral hypothalamus. They are involved in the regulation of energy metabolism, neuroendocrine, sleep and waking. Recently, more and more evidence have shown that orexins play a key role in the stress and reward including drug addiction. The evidence was sumarized, showing that orexin neurons are well positioned to regulate stress-related neural systems, and orexin systems are involved in the physiological, neuroencocrine, psychological and behavioral process of stress. More recently, the role of orexins in stress-induced relapse of drug abuse has been established. All these evidence implicated that orexin system play a critical role in the process of stress, and their role in stress is dependent on the type of stress, their distribution and connection to other stress-related neurotransmitter systems. |
关键词 | orexins (hypocretins) stress drug addiction relapse |
2010-07-01 | |
语种 | 英语 |
发表期刊 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS |
ISSN | 1000-3282 |
卷号 | 37期号:7页码:713-719 |
期刊论文类型 | Article |
收录类别 | SCI |
WOS记录号 | WOS:000280330600003 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/13691 |
专题 | 中国科学院心理研究所回溯数据库(1956-2010) |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
第一作者单位 | 中国科学院心理健康重点实验室 |
推荐引用方式 GB/T 7714 | Wei Chu-Guang,Li Yong-Hui,Han Jin,et al. The Role of Orexin in Stress[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2010,37(7):713-719. |
APA | Wei Chu-Guang,Li Yong-Hui,Han Jin,Wang Hui-Ying,&Sui Nan.(2010).The Role of Orexin in Stress.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,37(7),713-719. |
MLA | Wei Chu-Guang,et al."The Role of Orexin in Stress".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 37.7(2010):713-719. |
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