The Role of Orexin in Stress
Wei Chu-Guang1,2; Li Yong-Hui1; Han Jin1,2; Wang Hui-Ying1,2; Sui Nan1
摘要Orexins (hypocretins) are novel neuropeptides released by some neurons identified in lateral hypothalamus. They are involved in the regulation of energy metabolism, neuroendocrine, sleep and waking. Recently, more and more evidence have shown that orexins play a key role in the stress and reward including drug addiction. The evidence was sumarized, showing that orexin neurons are well positioned to regulate stress-related neural systems, and orexin systems are involved in the physiological, neuroencocrine, psychological and behavioral process of stress. More recently, the role of orexins in stress-induced relapse of drug abuse has been established. All these evidence implicated that orexin system play a critical role in the process of stress, and their role in stress is dependent on the type of stress, their distribution and connection to other stress-related neurotransmitter systems.
关键词orexins (hypocretins) stress drug addiction relapse
2010-07-01
语种英语
发表期刊PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
ISSN1000-3282
卷号37期号:7页码:713-719
期刊论文类型Article
收录类别SCI
WOS记录号WOS:000280330600003
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/13691
专题中国科学院心理研究所回溯数据库(1956-2010)
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
第一作者单位中国科学院心理健康重点实验室
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Wei Chu-Guang,Li Yong-Hui,Han Jin,et al. The Role of Orexin in Stress[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2010,37(7):713-719.
APA Wei Chu-Guang,Li Yong-Hui,Han Jin,Wang Hui-Ying,&Sui Nan.(2010).The Role of Orexin in Stress.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,37(7),713-719.
MLA Wei Chu-Guang,et al."The Role of Orexin in Stress".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 37.7(2010):713-719.
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