| The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells | |
| Li, Lianqin1; Yu, Ai-Qun2,3,4 | |
| 摘要 | The mammalian peroxiredoxin (PRX) family contains six members that provide antioxidant defense in different cell types by removing reactive oxygen species (ROS) through conserved active cysteines. Different from other members, PRX3 is predominantly located in mitochondria, a major apoptosis mediator. The purpose of this review is to summarize the findings on PRX3 concerning its role in ROS removal, apoptosis, and chemoresistance of cancer cells. |
| 关键词 | Peroxiredoxin (PRX) Reactive oxygen species (ROS) Oxidative stress Apoptosis Cancer |
| 2015-12-01 | |
| 语种 | 英语 |
| 发表期刊 | JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
 |
| ISSN | 0171-5216 |
| 卷号 | 141期号:12页码:2071-2077 |
| 期刊论文类型 | Review |
| 收录类别 | SCI |
| WOS记录号 | WOS:000364224800001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.psych.ac.cn/handle/311026/15311 |
| 专题 | 健康与遗传心理学研究室 |
| 作者单位 | 1.Binzhou Med Univ, Dept Obstet & Gynecol, Yantai Affiliated Hosp, Yantai 264100, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 4.Beijing Technol & Business Univ, Canvard Coll, Beijing 101118, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Lianqin,Yu, Ai-Qun. The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells[J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,2015,141(12):2071-2077. |
| APA | Li, Lianqin,&Yu, Ai-Qun.(2015).The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells.JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,141(12),2071-2077. |
| MLA | Li, Lianqin,et al."The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells".JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 141.12(2015):2071-2077. |
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