中文版 | English

在结果中检索

PSYCH OpenIR

浏览/检索结果: 共22条，第1-10条 帮助

已选(0)清除 条数/页：   排序方式：
The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus 期刊论文
BRAIN IMAGING AND BEHAVIOR, 2024, 页码: 9
作者:  Hu, Yuanyuan;  Zhao, Jingjie;  Jin, Yuening;  Du, Yi;  Zhao, Qian;  Xu, Shuai;  Li, Li;  Zhou, Yuan
收藏  |  浏览/下载：25/0  |  提交时间：2024/11/18
Globus Pharyngeus  Resting-state functional magnetic resonance imaging  Functional connectivity  Thalamus  
Cross-ancestry genome-wide association studies of brain imaging phenotypes 期刊论文
NATURE GENETICS, 2024, 页码: 31
作者:  Fu, Jilian;  Zhang, Quan;  Wang, Jianhua;  Wang, Meiyun;  Zhang, Bing;  Zhu, Wenzhen;  Qiu, Shijun;  Geng, Zuojun;  Cui, Guangbin;  Yu, Yongqiang;  Liao, Weihua;  Zhang, Hui;  Gao, Bo;  Xu, Xiaojun;  Han, Tong;  Yao, Zhenwei;  Qin, Wen;  Liu, Feng;  Liang, Meng;  Wang, Sijia;  Xu, Qiang;  Xu, Jiayuan;  Zhang, Peng;  Li, Wei;  Shi, Dapeng;  Wang, Caihong;  Lui, Su;  Yan, Zhihan;  Chen, Feng;  Zhang, Jing;  Li, Jiance;  Shen, Wen;  Miao, Yanwei;  Wang, Dawei;  Xian, Junfang;  Gao, Jia-Hong;  Zhang, Xiaochu;  Xu, Kai;  Zuo, Xi-Nian;  Zhang, Longjiang;  Ye, Zhaoxiang;  Cheng, Jingliang;  Li, Mulin Jun;  Yu, Chunshui;  Zhang, Quan;  Wang, Junping;  Zhang, Xue;  Suo, Xinjun;  Yuan, Congcong;  Ji, Yuan;  Xue, Hui;  Gao, Tianying;  Liu, Junpeng;  Li, Yanjun;  Guo, Xi;  Xu, Lixue;  Zhu, Jiajia;  Liu, Huaigui;  Zhao, Fangshi;  Sun, Jie;  Xu, Yongjie;  Cai, Huanhuan;  Tang, Jie;  Zhang, Yaodan;  Xiong, Yongqin;  Sun, Xianting;  Pan, Nannan;  Zhang, Xue;  Yang, Jiayang;  Liu, Nana;  Wen, Ya;  Zhu, Dan;  Wu, Bingjie;  Zhu, Wenshuang;  Diao, Qingqing;  Cao, Yujuan;  Yang, Bingbing;  Guo, Lining;  Xie, Yingying;  Lin, Jiahui;  Li, Zhimin;  Zhang, Yan;  Xue, Kaizhong;  Wang, Zirui;  Shen, Junlin;  Zhang, Xuejun;  Ding, Hao;  Su, Qian;  Zhang, Shijie;  Ma, Lun;  Bai, Yan;  Guan, Min;  Wei, Wei;  Miao, Peifang;  Duan, Fuhong;  Guo, Yafei;  Wang, Weijian;  Zheng, Lijuan;  Lin, Li;  Wang, Yunfei;  Zhang, Han;  Zhang, Xinyuan;  Qing, Zhao;  Wu, Sichu;  Wang, Junxia;  Sun, Yi;  He, Yang;  Zhang, Zhe;  Wang, Yin-Shan;  Zhou, Quan;  Tian, Tian;  Liang, Yi;  Liu, Yujie;  Zeng, Hui;  Chen, Jingxian;  Ge, Haitao;  Xu, Peng;  Lu, Cailuan;  Wu, Chen;  Yang, Xiaoying;  Wang, Yuzhao;  Wu, Yankai;  Feng, Xuran;  Li, Ling;  Gao, Duo;  Zha, Rujing;  Li, Ying;  Yang, Lizhuang;  Chen, Ying;  Zuo, Ling;  Ge, Jianqiao;  Yang, Guoyuan;  Wang, Wen;  Yan, Linfeng;  Yang, Yang;  Zhang, Jin;  Wang, Qian;  Qu, Xiaoxia;  Wang, Ying;  Yuan, Fei;  Hu, Li;  Li, Jizhen;  Wang, Weiwei;  Zhou, Yujing;  Long, Miaomiao;  Liu, Lihua;  Li, Xiaohu;  Li, Xiaoshu;  Yang, Yunjun;  Xia, Nengzhi;  Yang, Shuai;  Zhang, Youming;  Liu, Guangyao;  Ma, Laiyang;  Wang, Xiaochun;  Lei, Ying;  Zhang, Gang;  Yuan, Kang;  Xu, Jingjing;  Guan, Xiaojun;  Lin, Yuankai;  Chen, Huijuan;  Fu, Yuchuan;  Lu, Yi;  Guo, Jun;  Lu, Hao;  Wu, Yue
Adobe PDF(14637Kb)  |  收藏  |  浏览/下载：193/0  |  提交时间：2024/06/29
A longitudinal resource for population neuroscience of school-age children and adolescents in China 期刊论文
SCIENTIFIC DATA, 2023, 卷号: 10, 期号: 1, 页码: 24
作者:  Fan, Xue-Ru;  Wang, Yin-Shan;  Chang, Da;  Yang, Ning;  Rong, Meng-Jie;  Zhang, Zhe;  He, Ye;  Hou, Xiaohui;  Zhou, Quan;  Gong, Zhu-Qing;  Cao, Li-Zhi;  Dong, Hao-Ming;  Nie, Jing-Jing;  Chen, Li-Zhen;  Zhang, Qing;  Zhang, Jia-Xin;  Zhang, Lei;  Li, Hui-Jie;  Bao, Min;  Chen, Antao;  Chen, Jing;  Chen, Xu;  Ding, Jinfeng;  Dong, Xue;  Du, Yi;  Feng, Chen;  Feng, Tingyong;  Fu, Xiaolan;  Ge, Li-Kun;  Hong, Bao;  Hu, Xiaomeng;  Huang, Wenjun;  Jiang, Chao;  Li, Li;  Li, Qi;  Li, Su;  Liu, Xun;  Mo, Fan;  Qiu, Jiang;  Su, Xue-Quan;  Wei, Gao-Xia;  Wu, Yiyang;  Xia, Haishuo;  Yan, Chao-Gan;  Yan, Zhi-Xiong;  Yang, Xiaohong;  Zhang, Wenfang;  Zhao, Ke;  Zhu, Liqi;  Zuo, Xi-Nian;  Zhu, Xing-Ting;  Hou, Xiao-Hui;  Wang, Ping;  Zhang, Yi-Wen;  Sui, Dan-Yang;  Xu, Ting;  Jiang, Lili;  Zhou, Yuan;  Zhuo, Yan;  Zuo, Zhentao;  Ke, Li;  Wang, Fei;  Castellanos, F. Xavier;  Milham, Michael Peter;  Zang, Yu-Feng;  Adamson, Chris;  Adler, Sophie;  Alexander-Bloch, Aaron F.;  Anagnostou, Evdokia;  Anderson, Kevin M.;  Areces-Gonzalez, Ariosky;  Astle, Duncan E.;  Auyeung, Bonnie;  Ayub, Muhammad;  Ball, Gareth;  Baron-Cohen, Simon;  Beare, Richard;  Bedford, Saashi A.;  Benegal, Vivek;  Bethlehem, Richard A. I.;  Beyer, Frauke;  Bin Bae, Jong;  Blangero, John;  Cabez, Manuel Blesa;  Boardman, James P.;  Borzage, Matthew;  Bosch-Bayard, Jorge F.;  Bourke, Niall;  Bullmore, Edward T.;  Calhoun, Vince D.;  Chakravarty, Mallar M.;  Chen, Christina;  Chertavian, Casey;  Chetelat, Gael;  Chong, Yap S.;  Corvin, Aiden;  Costantino, Manuela;  Courchesne, Eric;  Crivello, Fabrice;  Cropley, Vanessa L.;  Crosbie, Jennifer;  Crossley, Nicolas;  Delarue, Marion;  Delorme, Richard;  Desrivieres, Sylvane;  Devenyi, Gabriel;  Di Biase, Maria A.;  Dolan, Ray;  Donald, Kirsten A.;  Donohoe, Gary;  Dunlop, Katharine;  Edwards, Anthony D.;  Elison, Jed T.;  Ellis, Cameron T.;  Elman, Jeremy A.;  Eyler, Lisa;  Fair, Damien A.;  Fletcher, Paul C.;  Fonagy, Peter;  Franz, Carol E.;  Galan-Garcia, Lidice;  Gholipour, Ali;  Giedd, Jay;  Gilmore, John H.;  Glahn, David C.;  Goodyer, Ian M.;  Grant, P. E.;  Groenewold, Nynke A.;  Gunning, Faith M.;  Gur, Raquel E.;  Gur, Ruben C.;  Hammill, Christopher F.;  Hansson, Oskar;  Hedden, Trey;  Heinz, Andreas;  Henson, Richard N.;  Heuer, Katja;  Hoare, Jacqueline;  Holla, Bharath;  Holmes, Avram J.;  Huang, Hao;  Im, Kiho;  Ipser, Jonathan;  Jack, Clifford R., Jr.;  Jackowski, Andrea P.;  Jia, Tianye;  Jones, David T.;  Jones, Peter B.;  Kahn, Rene S.;  Karlsson, Hasse;  Karlsson, Linnea;  Kawashima, Ryuta;  Kelley, Elizabeth A.;  Kern, Silke;  Kim, Ki-Woong;  Kitzbichler, Manfred G.;  Kremen, William S.;  Lalonde, Francois;  Landeau, Brigitte;  Lerch, Jason;  Lewis, John D.;  Li, Jiao;  Liao, Wei;  Paz-Linares, Deirel;  Liston, Conor;  Lombardo, Michael V.;  Lv, Jinglei;  Mallard, Travis T.;  Mathias, Samuel R.;  Marcelis, Machteld;  Mazoyer, Bernard;  McGuire, Philip;  Meaney, Michael J.;  Mechelli, Andrea;  Misic, Bratislav;  Morgan, Sarah E.;  Mothersill, David;  Ortinau, Cynthia;  Ossenkoppele, Rik;  Ouyang, Minhui;  Palaniyappan, Lena;  Paly, Leo;  Pan, Pedro M.;  Pantelis, Christos;  Park, Min Tae M.;  Paus, Tomas;  Pausova, Zdenka;  Binette, Alexa Pichet;  Pierce, Karen;  Qian, Xing;  Qiu, Anqi;  Raznahan, Armin;  Rittman, Timothy;  Rodrigue, Amanda;  Rollins, Caitlin K.;  Romero-Garcia, Rafael;  Ronan, Lisa;  Rosenberg, Monica D.;  Rowitch, David H.;  Salum, Giovanni A.;  Satterthwaite, Theodore D.;  Schaare, H. Lina;  Schachar, Russell J.;  Scholl, Michael;  Schultz, Aaron P.;  Seidlitz, Jakob;  Sharp, David;  Shinohara, Russell T.;  Skoog, Ingmar;  Smyser, Christopher D.;  Sperling, Reisa A.;  Stein, Dan J.;  Stolicyn, Aleks;  Suckling, John;  Sullivan, Gemma;  Thyreau, Benjamin;  Toro, Roberto;  Traut, Nicolas;  Tsvetanov, Kamen A.;  Turk-Browne, Nicholas B.;  Tuulari, Jetro J.;  Tzourio, Christophe;  Vachon-Presseau, Etienne;  Valdes-Sosa, Mitchell J.;  Valdes-Sosa, Pedro A.;  Valk, Sofie L.;  van Amelsvoort, Therese;  Vandekar, Simon N.;  Vasung, Lana;  Vertes, Petra E.;  Victoria, Lindsay W.;  Villeneuve, Sylvia;  Villringer, Arno;  Vogel, Jacob W.;  Wagstyl, Konrad;  Warfield, Simon K.;  Warrier, Varun;  Westman, Eric;  Westwater, Margaret L.;  Whalley, Heather C.;  White, Simon R.;  Witte, A. Veronica;  Yeo, B. T. Thomas;  Yun, Hyuk Jin;  Zalesky, Andrew;  Zar, Heather J.;  Zettergren, Anna;  Zhou, Juan H.;  Ziauddeen, Hisham;  Zugman, Andre
Adobe PDF(4499Kb)  |  收藏  |  浏览/下载：296/0  |  提交时间：2023/12/11
Neural correlates of audiovisual speech synchrony perception and its relationship with autistic traits 期刊论文
PSYCH JOURNAL, 2022, 页码: 10
作者:  Zhou, Han-yu;  Zhang, Yi-jing;  Hu, Hui-xin;  Yan, Yong-jie;  Wang, Ling-ling;  Lui, Simon S. Y.;  Chan, Raymond C. K.
Adobe PDF(1443Kb)  |  收藏  |  浏览/下载：148/0  |  提交时间：2023/01/16
anterior insula  audiovisual speech  autistic traits  synchrony perception  
Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder 期刊论文
TRANSLATIONAL PSYCHIATRY, 2022, 卷号: 12, 期号: 1, 页码: 9
作者:  Ding, Yu-Dan;  Chen, Xiao;  Chen, Zuo-Bing;  Li, Le;  Li, Xue-Ying;  Castellanos, Francisco Xavier;  Bai, Tong-Jian;  Bo, Qi-Jing;  Cao, Jun;  Chang, Zhi-Kai;  Chen, Guan-Mao;  Chen, Ning-Xuan;  Chen, Wei;  Cheng, Chang;  Cheng, Yu-Qi;  Cui, Xi-Long;  Duan, Jia;  Fang, Yi-Ru;  Gong, Qi-Yong;  Hou, Zheng-Hua;  Hu, Lan;  Kuang, Li;  Li, Feng;  Li, Hui-Xian;  Li, Kai-Ming;  Li, Tao;  Liu, Yan-Song;  Liu, Zhe-Ning;  Long, Yi-Cheng;  Lu, Bin;  Luo, Qing-Hua;  Meng, Hua-Qing;  Peng, Dai-Hui;  Qiu, Hai-Tang;  Qiu, Jiang;  Shen, Yue-Di;  Shi, Yu-Shu;  Si, Tian-Mei;  Tang, Yan-Qing;  Wang, Chuan-Yue;  Wang, Fei;  Wang, Kai;  Wang, Li;  Wang, Xiang;  Wang, Ying;  Wang, Yu-Wei;  Wu, Xiao-Ping;  Wu, Xin-Ran;  Xie, Chun-Ming;  Xie, Guang-Rong;  Xie, Hai-Yan;  Xie, Peng;  Xu, Xiu-Feng;  Yang, Hong;  Yang, Jian;  Yao, Jia-Shu;  Yao, Shu-Qiao;  Yin, Ying-Ying;  Yuan, Yong-Gui;  Zang, Yu-Feng;  Zhang, Ai-Xia;  Zhang, Hong;  Zhang, Ke-Rang;  Zhang, Lei;  Zhang, Zhi-Jun;  Zhao, Jing-Ping;  Zhou, Ru-Bai;  Zhou, Yi-Ting;  Zhu, Jun-Juan;  Zhu, Zhi-Chen;  Zou, Chao-Jie;  Zuo, Xi-Nian;  Yan, Chao-Gan;  Guo, Wen-Bin
Adobe PDF(1940Kb)  |  收藏  |  浏览/下载：672/1  |  提交时间：2022/07/18
老年主观记忆障碍患者轻度认知障碍发生情况及影响因素分析 期刊论文
中华现代护理杂志, 2022, 卷号: 28, 期号: 4, 页码: 470-477
作者:  杨存美;  李娟;  胡亦新;  周滢;  马虹颖;  靳楠楠;  王怡丹
Adobe PDF(1779Kb)  |  收藏  |  浏览/下载：317/1  |  提交时间：2022/04/11
老年人  主观记忆障碍  轻度认知障碍  影响因素  
Risk of First-Episode Schizophrenia in Aged Adults Increased During COVID-19 Outbreak 期刊论文
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION, 2021, 页码: 11
作者:  Hu, Wei;  Su, Li;  Li, Deyong;  Zhou, Yi;  Zhu, Jing
Adobe PDF(705Kb)  |  收藏  |  浏览/下载：491/0  |  提交时间：2021/11/12
Schizophrenia  COVID-19  Mental disorders  Age  Public health  Risk factor  
Disrupted intrinsic functional brain topology in patients with major depressive disorder 期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 9
作者:  Yang, Hong;  Chen, Xiao;  Chen, Zuo-Bing;  Li, Le;  Li, Xue-Ying;  Castellanos, Francisco Xavier;  Bai, Tong-Jian;  Bo, Qi-Jing;  Cao, Jun;  Chang, Zhi-Kai;  Chen, Guan-Mao;  Chen, Ning-Xuan;  Chen, Wei;  Cheng, Chang;  Cheng, Yu-Qi;  Cui, Xi-Long;  Duan, Jia;  Fang, Yiru;  Gong, Qi-Yong;  Guo, Wen-Bin;  Hou, Zheng-Hua;  Hu, Lan;  Kuang, Li;  Li, Feng;  Li, Hui-Xian;  Li, Kai-Ming;  Li, Tao;  Liu, Yan-Song;  Liu, Zhe-Ning;  Long, Yi-Cheng;  Lu, Bin;  Luo, Qing-Hua;  Meng, Hua-Qing;  Peng, Daihui;  Qiu, Hai-Tang;  Qiu, Jiang;  Shen, Yue-Di;  Shi, Yu-Shu;  Si, Tian-Mei;  Tang, Yan-Qing;  Wang, Chuan-Yue;  Wang, Fei;  Wang, Kai;  Wang, Li;  Wang, Xiang;  Wang, Ying;  Wang, Yu-Wei;  Wu, Xiao-Ping;  Wu, Xin-Ran;  Xie, Chun-Ming;  Xie, Guang-Rong;  Xie, Hai-Yan;  Xie, Peng;  Xu, Xiu-Feng;  Yang, Jian;  Yao, Jia-Shu;  Yao, Shu-Qiao;  Yin, Ying-Ying;  Yuan, Yong-Gui;  Zang, Yu-Feng;  Zhang, Ai-Xia;  Zhang, Hong;  Zhang, Ke-Rang;  Zhang, Lei;  Zhang, Zhi-Jun;  Zhao, Jing-Ping;  Zhou, Rubai;  Zhou, Yi-Ting;  Zhu, Jun-Juan;  Zhu, Zhi-Chen;  Zou, Chao-Jie;  Zuo, Xi-Nian;  Yan, Chao-Gan
Adobe PDF(2476Kb)  |  收藏  |  浏览/下载：629/0  |  提交时间：2021/09/24
Disrupted hemispheric connectivity specialization in patients with major depressive disorder: Evidence from the REST-meta-MDD Project 期刊论文
JOURNAL OF AFFECTIVE DISORDERS, 2021, 卷号: 284, 页码: 217-228
作者:  Ding, Yu-Dan;  Yang, Ru;  Yan, Chao-Gan;  Chen, Xiao;  Bai, Tong-Jian;  Bo, Qi-Jing;  Chen, Guan-Mao;  Chen, Ning-Xuan;  Chen, Tao-Lin;  Chen, Wei;  Cheng, Chang;  Cheng, Yu-Qi;  Cui, Xi-Long;  Duan, Jia;  Fang, Yi-Ru;  Gong, Qi-Yong;  Hou, Zheng-Hua;  Hu, Lan;  Kuang, Li;  Li, Feng;  Li, Tao;  Liu, Yan-Song;  Liu, Zhe-Ning;  Long, Yi-Cheng;  Luo, Qing-Hua;  Meng, Hua-Qing;  Peng, Dai-Hui;  Qiu, Hai-Tang;  Qiu, Jiang;  Shen, Yue-Di;  Shi, Yu-Shu;  Tang, Yanqing;  Wang, Chuan-Yue;  Wang, Fei;  Wang, Kai;  Wang, Li;  Wang, Xiang;  Wang, Ying;  Wu, Xiao-Ping;  Wu, Xin-Ran;  Xie, Chun-Ming;  Xie, Guang-Rong;  Xie, Hai-Yan;  Xie, Peng;  Xu, Xiu-Feng;  Yang, Hong;  Yang, Jian;  Yao, Jia-Shu;  Yao, Shu-Qiao;  Yin, Ying-Ying;  Yuan, Yong-Gui;  Zhang, Ai-Xia;  Zhang, Hong;  Zhang, Ke-Rang;  Zhang, Lei;  Zhang, Zhi-Jun;  Zhou, Ru-Bai;  Zhou, Yi-Ting;  Zhu, Jun-Juan;  Zou, Chao-Jie;  Si, Tian-Mei;  Zang, Yu-Feng;  Zhao, Jing-Ping;  Guo, Wen-Bin
Adobe PDF(2897Kb)  |  收藏  |  浏览/下载：685/0  |  提交时间：2021/04/19
Major depressive disorder  hemispheric asymmetry  parameter of asymmetry  fMRI Abbreviations ACC, Anterior cingulate gyrus  DLPFC, Dorsolateral prefrontal cortex  DMN, Default mode network  DPARSF, Data Processing Assistant for Resting-State fMRI  DSM, Diagnosic and Statistical Manual of Mental Disorders  EEG, Electroencephalographic  FC, Functional connectivity  FDR, False discovery rate  FEDN, First-episode, drug-naive  FEF, Frontal eye fields  fMRI, Functional magnetic resonance imaging  HAMD, Hamilton Depression Rating Scale  HC, Healthy control  IFG, Inferior frontal gyrus  IPL, Inferior parietal lobule  IPS/SPL, Intraparietal sulcus/superior parietal lobule  LMM, Linear mixed model  MDD, Major depressive disorder  MFG, Middle frontal gyrus  MTG, Middle temporal gyrus  PAS, Parameter of asymmetry  PCC, Posterior cingulate cortex  PET, Positron emission tomography  ROIs, Regions of interest  rs-fMRI, Resting-state fMRI  rTMS, repetitive transcranial magnetic stimulation  STS, Superior temporal sulcus  VMHC, Voxel-mirrored homotopic connectivity  
Biotypes of major depressive disorder: Neuroimaging evidence from resting-state default mode network patterns 期刊论文
NeuroImage: Clinical, 2021, 卷号: 28
作者:  Liang, Sugai;  Deng, Wei;  Li, Xiaojing;  Greenshaw, Andrew J.;  Wang, Qiang;  Li, Mingli;  Ma, Xiaohong;  Bai, Tong-Jian;  Bo, Qi-Jing;  Cao, Jun;  Chen, Guan-Mao;  Chen, Wei;  Cheng, Chang;  Cheng, Yu-Qi;  Gui, Xi-Long;  Duan, Jia;  Fang, Yi-Ru;  Gong, Qi-Yong;  Guo, Wen-Bin;  Hou, Zheng-Hua;  Hu, Lan;  Kuang, Li;  Li, Feng;  Li, Kai-Ming;  Liu, Yan-Song;  Liu, Zhe-Ning;  Long, Yi-Cheng;  Luo, Qing-Hua;  Meng, Hua-Qing;  Peng, Dai-Hui;  Qiu, Hai-Tang;  Qiu, Jiang;  Shen, Yue-Di;  Shi, Yu-Shu;  Si, Tian-Mei;  Wang, Chuan-Yue;  Wang, Fei;  Wang, Kai;  Wang, Li;  Wang, Xiang;  Wang, Ying;  Wu, Xiao-Ping;  Wu, Xin-Ran;  Xie, Chun-Ming;  Xie, Guang-Rong;  Xie, Hai-Yan;  Xie, Peng;  Xu, Xiu-Feng;  Yang, Hong;  Yang, Jian;  Yu, Hua;  Yao, Jia-Shu;  Yao, Shu-Qiao;  Yin, Ying-Ying;  Yuan, Yong-Gui;  Zang, Yu-Feng;  Zhang, Ai-Xia;  Zhang, Hong;  Zhang, Ke-Rang;  Zhang, Zhi-Jun;  Zhao, Jing-Ping;  Zhou, Ru-Bai;  Zhou, Yi-Ting;  Zou, Chao-Jie;  Zuo, Xi-Nian;  Yan, Chao-Gan;  Li, Tao
Adobe PDF(2543Kb)  |  收藏  |  浏览/下载：431/0  |  提交时间：2021/11/18
Biotypes  Default mode network  Major depressive disorder  Resting-state fMRI  Machine learning